4-碘基-3-硝基苯甲醚合成路线 （共 16 条）
反应条件
FeCl3·6H2O; carbon; hydrazine hydrate in methanol 2 h; Reflux;
参考文献
Wetzel, Alexander; Gagosz, Fabien
Angewandte Chemie - International Edition, 2011 , vol. 50, # 32 p. 7354 - 7358
反应条件
copper; bis(dibenzylideneacetone)-palladium(0) in dimethyl sulfoxide
T=50°C; Ullmann cross-coupling; 1 h;
参考文献
Banwell, Martin G.; Kelly, Brian D.; Kokas, Okanya J.; Lupton, David W.
Organic Letters, 2003 , vol. 5, # 14 p. 2497 - 2500
反应条件
copper(l) iodide; ethyl acetoacetate; sodium hydride in N,N-dimethyl-formamide
T=100°C; 4 h;
参考文献
Thiruvikraman, Singanallore V.; Suzuki, Hitomi
Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 5 p. 1597 - 1598
反应条件
1: With phenyl-magnesium chloride in tetrahydrofuran
T=-60°C; 0.0833333 h;
2: With boric acid trimethyl ester in tetrahydrofuran
T=-60°C; 0.5 h;
3: With hydrogenchloride in tetrahydrofuran
T=-20°C;
参考文献
Collibee, Scott E.; Yu, Jiaxin
Tetrahedron Letters, 2005 , vol. 46, # 26 p. 4453 - 4455
反应条件
hydrogenchloride in tetrahydrofuran
参考文献
Harper, Steven; Summa, Vincenzo; Liverton, Nigel J.; McCauley, John A.; Butcher, John W.; Di Filippo, Marcello; Di Francesco, Maria Emilia; Ferrara, Marco; Romano, Joseph J.; Rudd, Michael T.
Patent: US2010/183551 A1, 2010 ;
反应条件
1: 79 percent / hydrazine monohydrate; graphite / ethanol / 8 h / Heating
2: PdCl2(dppf) / 6 h / 120 °C / 12928.7 Torr
View Scheme
参考文献
Haddad, Nizar; Tan, Jonathan; Farina, Vittorio
Journal of Organic Chemistry, 2006 , vol. 71, # 13 p. 5031 - 5034
