1-碘-3,4-亚甲基二氧基苯合成路线 （共 31 条）
反应条件
1: 4-oxo-4H-1-benzopyran With (2,2,6,6-tetramethylpiperidine)2Zn·2MgCl2·2LiCl in tetrahydrofuran
T=-30°C; 1 h; Inert atmosphere;
2: 4-iodo-1,2-methylenedioxybenzene With bis(dibenzylideneacetone)-palladium(0); P(2-furyl)3 in tetrahydrofuran
T=25°C; Negishi cross-coupling reaction; 1 h; Inert atmosphere; regioselective reaction;
参考文献
Klier, Lydia; Bresser, Tomke; Nigst, Tobias A.; Karaghiosoff, Konstantin; Knochel, Paul
Journal of the American Chemical Society, 2012 , vol. 134, # 33 p. 13584 - 13587
