1-甲基-4-氮杂芴-9-酮合成路线 （共 24 条）
反应条件
1: 30 percent / 3,4-dimethyl-2-phenylpyridine / benzene
2: 81 percent / O2, 20percent aq. NaOH / dimethylsulfoxide / 3 h / 30 - 40 °C
View Scheme
参考文献
Prostakov, N. S.; Soldatenkov, A. T.; Radzhan, P. K.; Fedorov, V. O.; Fomichev, A. A.; Rezakov, V. A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982 , vol. 18, # 4 p. 390 - 394
Khimiya Geterotsiklicheskikh Soedinenii, 1982 , vol. 18, # 4 p. 513 - 517
反应条件
1.1: tetrahydrofuran / -50 °C
1.2: 4 h / 20 °C
1.3: 2 h / 0 - 20 °C
2.1: PPA / 210 °C / |Heating
3.1: sodium acetate; palladium 10 on activated carbon; hydrogen / methanol / 760.05 Torr
View Scheme
参考文献
Zhang, Song; Liao, Lian-Yan; Zhang, Fang; Duan, Xin-Fang
Journal of Organic Chemistry, 2013 , vol. 78, # 6 p. 2720 - 2725
反应条件
1.1: tetrahydrofuran / -50 °C
1.2: 4 h / 20 °C
1.3: 2 h / 0 - 20 °C
2.1: PPA / 210 °C / |Heating
3.1: sodium acetate; palladium 10 on activated carbon; hydrogen / methanol / 760.05 Torr
View Scheme
参考文献
Zhang, Song; Liao, Lian-Yan; Zhang, Fang; Duan, Xin-Fang
Journal of Organic Chemistry, 2013 , vol. 78, # 6 p. 2720 - 2725
反应条件
in methanol; sodium tetrahydroborate; dichloromethane
参考文献
BASF Aktiengesellschaft
Patent: US5637554 A1, 1997 ;
