4-溴-2-(三氟甲基)喹啉-3-羧酸甲酯合成路线 （共 4 条）
反应条件
potassium carbonate in acetone
T=25°C; 6 h;
参考文献
Marull, Marc; Schlosser, Manfred
European Journal of Organic Chemistry, 2003 , # 8 p. 1576 - 1588
反应条件
1: 88 percent / phosphorus oxybromide / 2 h / 150 °C
2: 88 percent / butyllithium; diisopropylamine / tetrahydrofuran; hexane / 2 h / -75 °C
3: 95 percent / potassium carbonate / acetone / 6 h / 25 °C
View Scheme
参考文献
Marull, Marc; Schlosser, Manfred
European Journal of Organic Chemistry, 2003 , # 8 p. 1576 - 1588
反应条件
1: 51 percent / polyphosphoric acid / 2 h / 150 °C
2: 88 percent / phosphorus oxybromide / 2 h / 150 °C
3: 88 percent / butyllithium; diisopropylamine / tetrahydrofuran; hexane / 2 h / -75 °C
4: 95 percent / potassium carbonate / acetone / 6 h / 25 °C
View Scheme
参考文献
Marull, Marc; Schlosser, Manfred
European Journal of Organic Chemistry, 2003 , # 8 p. 1576 - 1588
反应条件
1: 88 percent / butyllithium; diisopropylamine / tetrahydrofuran; hexane / 2 h / -75 °C
2: 95 percent / potassium carbonate / acetone / 6 h / 25 °C
View Scheme
参考文献
Marull, Marc; Schlosser, Manfred
European Journal of Organic Chemistry, 2003 , # 8 p. 1576 - 1588
