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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
588-72-7
合成路线
(共 268 条)
588-72-7
+
151-50-8
氰化钾
→
反应条件
1885-38-7
肉桂腈
+
24840-05-9
反应条件
7,N-dibenzyl ether; NiBr2(PPh3)2; triphenylphosphine; zinc in N,N-dimethyl-formamide T=50°C; 16 h; Yield given. Yields of byproduct given;
参考文献
Sakakibara, Yasumasa; Yadani, Nobuichi; Ibuki, Ichiro; Sakai, Mutsuji; Uchino, Norito
Chemistry Letters, 1982 , p. 1565 - 1566
588-72-7
+
544-92-3
氰化亚铜
→
反应条件
1885-38-7
肉桂腈
+
24840-05-9
反应条件
in N,N-dimethyl-formamide T=150°C; other solvent; Product distributionRate constant;
参考文献
Prochazka, Milos; Siroky, Miroslav
Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 6 p. 1765 - 1773
588-72-7
→
反应条件
1885-38-7
肉桂腈
+
24840-05-9
反应条件
in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=140°C; 72 h; other time; Product distribution;
参考文献
Prochazka, Milos; Siroky, Miroslav
Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 6 p. 1765 - 1773
588-72-7
+
619-55-6
对甲苯酰胺
→
反应条件
16155-60-5
反应条件
1: potassium carbonate; copper(l) iodide; N-methyl-2-(methylamino)ethylamine / tetrahydrofuran / 18 h / 80 °C / |Inert atmosphere 2: copper(ll) bromide; tetrabutylammomium bromide; dipotassium peroxodisulfate; 3-pyridinecarboxylic acid ethyl ester / acetonitrile / 24 h / 20 °C / |Inert atmosphere View Scheme
参考文献
Cheung, Chi Wai; Buchwald, Stephen L.
Journal of Organic Chemistry, 2012 , vol. 77, # 17 p. 7526 - 7537
588-72-7
+
20277-69-4
→
反应条件
15436-11-0
反应条件
copper(l) iodide; [bmim]BF4; proline potassium salt T=110°C; 10 h;
参考文献
Bao, Weiliang; Wang, Congna
Journal of Chemical Research, 2006 , # 6 p. 396 - 397
588-72-7
+
67-68-5
→
反应条件
15436-11-0
反应条件
copper(I) oxide; potassium tert-butylate; oxygen; acetylacetone T=130°C; 36 h;
参考文献
Yuan, Gaoqing; Zheng, Junhua; Gao, Xiaofang; Li, Xianwei; Huang, Liangbin; Chen, Huoji; Jiang, Huanfeng
Chemical Communications, 2012 , vol. 48, # 60 p. 7513 - 7515
588-72-7
→
反应条件
15436-11-0
反应条件
1: 96 percent / hexamethylphosphoric acid triamide / 1 h / Ambient temperature 2: H2O2 / acetic acid View Scheme
参考文献
Tiecco, Marcello; Testaferri, Lorenzo; Tingoli, Marco; Chianelli, Donatella; Montanucci, Manuela
Journal of Organic Chemistry, 1983 , vol. 48, # 25 p. 4795 - 4800
110-53-2
+
588-72-7
→
反应条件
14374-45-9
反应条件
(i) LiNEt2, THF, (ii) /BRN= 1730981/; Multistep reaction;
参考文献
Reisdorf,D.; Normant,H.
Organometallics in Chemical Synthesis, 1972 , vol. 1, p. 393 - 414
603-76-9
+
201230-82-2
+
588-72-7
→
反应条件
65136-45-0
反应条件
triethyl borane; tert.-butyl lithium; bis-triphenylphosphine-palladium(II) chloride 1.) THF, pentane, hexane, r.t., 1 h; -20 deg C, 1 h, 2.) xylene, 15 atm., 90 deg C, 20 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Ishikura; Terashima
Journal of Organic Chemistry, 1994 , vol. 59, # 9 p. 2634 - 2637
588-72-7
→
反应条件
73830-10-1
反应条件
1: 9 percent Chromat. / t-BuOK / FeCl2 / dimethylsulfoxide / 0.17 h / Ambient temperature 2: 75 percent / t-BuOK / dimethylsulfoxide / 0.33 h / Ambient temperature View Scheme
参考文献
Galli, Carlo; Gentili, Patrizia; Rappoport, Zvi
Journal of Organic Chemistry, 1994 , vol. 59, # 22 p. 6786 - 6795
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