1.1: palladium diacetate; triphenylphosphine; triethylamine / toluene / 12 h / 100 °C / |Inert atmosphere 2.1: B-chloro-diisopinocampheylborane / dichloromethane; n-heptane / 8 h / 25 °C 3.1: toluene; tetrahydrofuran / 4 h / 0 - 5 °C 4.1: N-ethyl-N,N-diisopropylamine / dichloromethane / -20 - -15 °C / |Inert atmosphere 5.1: n-butyllithium / tetrahydrofuran / 0.5 h / -15 °C / |Inert atmosphere 5.2: 5.5 h / -15 - -5 °C / |Inert atmosphere 6.1: palladium diacetate; triphenylphosphine; triethylamine / N,N-dimethyl-formamide / 110 °C 7.1: caustic lye / 12 h / 120 °C View Scheme

1.1: palladium diacetate; triphenylphosphine; triethylamine / toluene / 12 h / 100 °C / |Inert atmosphere 2.1: B-chloro-diisopinocampheylborane / dichloromethane; n-heptane / 8 h / 25 °C 3.1: toluene; tetrahydrofuran / 4 h / 0 - 5 °C 4.1: N-ethyl-N,N-diisopropylamine / dichloromethane / -20 - -15 °C / |Inert atmosphere 5.1: n-butyllithium / tetrahydrofuran / 0.5 h / -15 °C / |Inert atmosphere 5.2: 5.5 h / -15 - -5 °C / |Inert atmosphere 6.1: palladium diacetate; triphenylphosphine; triethylamine / N,N-dimethyl-formamide / 110 °C 7.1: caustic lye / 12 h / 120 °C 8.1: sodium hydroxide / methanol / 1 h / 25 °C View Scheme