N-(2-氨基乙基)噻吩-2-羧酰胺合成路线 (共 3 条)
反应条件
1: in dichloromethane
18 h;
2: in dichloromethane
4 h;
3: With trifluoroacetic acid
T=20°C; 2 h;
参考文献
Conn, P. Jeffrey; Lindsley, Craig W.; Wood, Michael R.; Gogliotti, Rocco D.; Niswender, Colleen M.; Melancon, Bruce J.; Lebois, Evan P.
Patent: US2011/172227 A1, 2011 ;
Location in patent: Page/Page column 48 ;
反应条件
ethylenediamine in water; toluene
参考文献
Imperial Chemical Industries PLC
Patent: US4520027 A1, 1985 ;
参考文献
Large; Smith
Journal of Medicinal Chemistry, 1982 , vol. 25, # 12 p. 1417 - 1422