(S)-(+)-二氢-5-(对甲苯基磺酰氧基甲基)-2(3H)-呋喃酮合成路线 （共 24 条）
反应条件
1: 93 percent / MgCl2*6H2O / N,N-dimethyl-acetamide / Heating 2: 58 percent / pyridine View Scheme
参考文献
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), , vol. 34, # 11 p. 2414 - 2415
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , # 11 p. 2605 - 2606
反应条件
1: 81.2 percent / pyridine / 5 °C 2: 50.6 percent / NaIO4, RuCl3*3H2O / acetonitrile; H2O; CCl4 / Ambient temperature View Scheme
参考文献
Agricultural and Biological Chemistry, , vol. 55, # 6 p. 1685 - 1686
反应条件
1: 81.2 percent / pyridine / 5 °C 2: 50.6 percent / NaIO4, RuCl3*3H2O / acetonitrile; H2O; CCl4 / Ambient temperature View Scheme
参考文献
Agricultural and Biological Chemistry, , vol. 55, # 6 p. 1685 - 1686
参考文献
Tetrahedron Letters, , vol. 23, # 33 p. 3401 - 3404
反应条件
pyridine; dimethylsulfide borane complex Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 38, # 19 p. 3479 - 3482
反应条件
1: 1.) KOH, 2.) 2M HCl / 2.) 50 deg C 2: 83 percent / pyridine / 0 °C View Scheme
参考文献
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 35, # 3 p. 155 - 162
参考文献
Journal of the Chemical Society, Chemical Communications, , # 20 p. 1399 - 1401
反应条件
PhCH2OLi; hydrogen 1.) THF, 2.) 10percent Pd/C, ether; Yield given. Multistep reaction;
参考文献
Ho, Pak-Tsun; Davies, Nancy
Synthesis, 1983 , # 6 p. 462
反应条件
tri-n-butyl-tin hydride; sodium iodide; 2,2'-azo-bisisobutyronitrile
参考文献
Harmange, Jean-Christophe; Figadere, Bruno; Hocquemiller, Reynald
Tetrahedron: Asymmetry, 1991 , vol. 2, # 5 p. 347 - 350
反应条件
1: 77 percent / LiAlH4 / tetrahydrofuran / 4 h / Ambient temperature 2: 23.7 percent / pyridine / Ambient temperature 3: 87 percent / immidazole / dimethylformamide / 16 h / Ambient temperature 4: 85 percent / Na / tetrahydrofuran; liquid ammonia / 1.5 h / -35 - -30 °C 5: 17 g / pyridine / 8 h / 0 °C 6: 74 percent / NaHCO3, NaI / acetone / 40 h / Heating 7: 82 percent / n-BuLi / hexamethylphosphoric acid triamide; tetrahydrofuran; hexane / 1 h / Ambient temperature 8: 79 percent / Na / tetrahydrofuran; liquid ammonia / 1 h 9: 431 mg / PCC, NaOAc / CH2Cl2 / 2.5 h / Ambient temperature 10: 570 mg / diisopropylamine / dimethylsulfoxide / Ambient temperature 11: 54 percent / pyrrolidine / hexamethylphosphoric acid triamide / Ambient temperature 12: 97 percent / PPTS / CH2Cl2 / Ambient temperature 13: 98 percent / 0.13N LiOH / methanol; H2O / 18 h / 50 °C 14: 93 percent / n-Bu4NF / tetrahydrofuran / 5 h / Ambient temperature 15: 47 percent / triphenylphosphine, dipyridyl disulfide / xylene / Ambient temperature 16: 35 mg / acetic acid; tetrahydrofuran; H2O / 4 h / 50 °C 17: TiCl4 / CH2Cl2 / 0.25 h / 0 °C View Scheme
参考文献
Kitahara; Mori
Tetrahedron, 1984 , vol. 40, # 15 p. 2935 - 2944
