1-(4-氯苯基)环己烷-1-羧酸合成路线 （共 6 条）
反应条件
hydrogenchloride; amalgamated zinc
参考文献
Journal of the American Chemical Society, , vol. 68, p. 828,831
反应条件
1: sodium hydride / dimethyl sulfoxide 2: sodium hydroxide / Trimethylene glycol View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 5 p. 1438 - 1441
反应条件
sodium hydroxide in Trimethylene glycol
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 5 p. 1438 - 1441
反应条件
1: sodium hydride / dimethyl sulfoxide 2: sodium hydroxide / Trimethylene glycol View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 5 p. 1438 - 1441
反应条件
thionyl chloride
T=65°C; 1 h;
参考文献
AMGEN INC.
Patent: WO2008/76427 A2, 2008 ;
Location in patent: Page/Page column 165 ;
反应条件
in diethyl ether
T=20°C; 24 h;
参考文献
Crane, Louis; Anastassiadou, Maria; Hage, Salome El; Stigliani, Jean Luc; Baziard-Mouysset, Genevieve; Payard, Marc; Leger, Jean Michel; Bizot-Espiard, Jean-Guy; Ktorza, Alain; Caignard, Daniel-Henri; Renard, Pierre
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 22 p. 7419 - 7433
