(3-氧代丙基)氨基甲酸叔丁酯合成路线 （共 15 条）
反应条件
1: Et3N / dioxane; H2O 2: CrO3, Py / CH2Cl2 View Scheme
参考文献
Tetrahedron, , vol. 31, p. 2940 - 2943
反应条件
1.1: silver benzoate; triethylamine / water / 16 h / 0 - 20 °C 2.1: diisobutylaluminium hydride / hexane; dichloromethane / 0.75 h / -90 - -85 °C / Inert atmosphere 2.2: -85 °C / Inert atmosphere View Scheme
参考文献
Tetrahedron Letters, , vol. 52, # 49 p. 6603 - 6605
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 17.3333 h; RefluxInert atmosphere; 2: With sodium sulfate decahydrate in tetrahydrofuran T=20°C; Inert atmosphere;
参考文献
Trapp, Sean G.; Leadbetter, Michael R.; Long, Daniel D.; Jiang, Lan; Axt, Sabine
Patent: US2009/247627 A1, 2009 ;
Location in patent: Page/Page column 17 ;
US 20090247627 A1
反应条件
1: 57 percent / NaBH3CN / methanol / 18 h / Ambient temperature 2: 78 percent View Scheme
参考文献
Bitan, Gal; Muller, Dan; Kasher, Ron; Gluhov, Evgenia V.; Gilon, Chaim
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 10 p. 1501 - 1510
反应条件
1: 4 Angstroem molecular sieves / tetrahydrofuran / 1 h
2: sodium cyanoborohydride, p-TsOH / tetrahydrofuran
3: 89 percent / Et3N / CH2Cl2 / Ambient temperature
4: 92 percent / H2 / 10percent Pd-C / methanol / 4 h / Ambient temperature
View Scheme
参考文献
Levchine; Rajan; Borloo; Bollaert; Hamers
Synthesis, 1994 , # 1 p. 37 - 39
