1: With isopropylmagnesium chloride in tetrahydrofuran T=-30°C; 0.5 h; 2: With sulfur dioxide in tetrahydrofuran T=-40°C; 0.5 h; 3: With sulfuryl dichloride in tetrahydrofuran T=-40 - 20°C;
参考文献
Pandya, Rina; Murashima, Takashi; Tedeschi, Livio; Barrett, Anthony G. M.
Journal of Organic Chemistry, 2003 , vol. 68, # 21 p. 8274 - 8276
1: diethyl malonate With N,N,N',N',N'',N''-hexamethylphosphoric triamide; sodium hydride in 1,4-dioxane; mineral oil T=20°C; 1 h; Inert atmosphere; 2: 4-bromo-1-iodobenzene With copper(I) bromide in 1,4-dioxane; mineral oil 5 h; Reflux;
1: 45 percent / Pd2(dba)3*CHCl3; NaO-t-Bu; P(t-Bu)3 / triethylamine / toluene; hexane / 4 h / 20 °C 2: Pd2(PhCN)2Cl2; CuI; P(t-Bu)3 / triethylamine / toluene; hexane / 15 h / 20 °C 3: 259 mg / tetra-n-butylammonium fluoride / tetrahydrofuran; CH2Cl2 / 2 h / 0 °C View Scheme
参考文献
McIlroy, Sean P.; Clo, Emiliano; Nikolajsen, Lars; Frederiksen, Peter K.; Nielsen, Christian B.; Mikkelsen, Kurt V.; Gothelf, Kurt V.; Ogilby, Peter R.
Journal of Organic Chemistry, 2005 , vol. 70, # 4 p. 1134 - 1146
