反应条件
1.1: n-butyllithium / tetrahydrofuran / 2.5 h / -78 °C / |Inert atmosphere 1.2: 0.5 h / -78 °C / |Inert atmosphere 2.1: tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide / 80 °C / |Inert atmosphere 3.1: trichlorophosphate / pyridine / 20 °C / |Inert atmosphere 4.1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C 5.1: hydrogenchloride / ethyl acetate / 1 h / 20 °C View Scheme
参考文献
Oslob, Johan D.; Johnson, Russell J.; Cai, Haiying; Feng, Shirley Q.; Hu, Lily; Kosaka, Yuko; Lai, Julie; Sivaraja, Mohanram; Tep, Samnang; Yang, Hanbiao; Zaharia, Cristiana A.; Evanchik, Marc J.; McDowell, Robert S.
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 1 p. 113 - 117