alpha-(2,4-二氯苯基)-1H-1,2,4-三唑-1-乙醇合成路线 （共 5 条）
反应条件
sodium tetrahydroborate in methanol
2 h;
参考文献
Wahbi, Y.; Caujolle, R.; Tournaire, C.; Payard, M.; Linas, M. D.; Seguela, J. P.
European Journal of Medicinal Chemistry, 1995 , vol. 30, # 12 p. 955 - 962
反应条件
sodium hydroxide; dimethyl sulfoxide
参考文献
Rohm and Haas Company
Patent: US4414210 A1, 1983 ;
反应条件
1: 35 percent / Et3N / acetonitrile / 4 h / Ambient temperature
2: 72 percent / NaBH4 / methanol / 2 h
View Scheme
参考文献
Wahbi, Y.; Caujolle, R.; Tournaire, C.; Payard, M.; Linas, M. D.; Seguela, J. P.
European Journal of Medicinal Chemistry, 1995 , vol. 30, # 12 p. 955 - 962
反应条件
1: Br2 / diethyl ether; CHCl3 / 0 - 20 °C
2: 35 percent / Et3N / acetonitrile / 4 h / Ambient temperature
3: 72 percent / NaBH4 / methanol / 2 h
View Scheme
参考文献
Wahbi, Y.; Caujolle, R.; Tournaire, C.; Payard, M.; Linas, M. D.; Seguela, J. P.
European Journal of Medicinal Chemistry, 1995 , vol. 30, # 12 p. 955 - 962
反应条件
thionyl chloride; sodium hydrogencarbonate in chloroform; ethyl acetate; toluene
参考文献
Bayer Aktiengesellschaft
Patent: US4102891 A1, 1978 ;
