3,3-二甲基-1-(1H-1,2,4-三唑-1-基)丁-2-酮合成路线 (共 15 条)
反应条件
1: NaH / tetrahydrofuran 2: NaBH4 / methanol View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 3 p. 425 - 430
反应条件
bromine; sodium acetate; acetic acid
参考文献
Zhong, Weihui; Sun, Xiuling; Su, Weike
Heteroatom Chemistry, 2008 , vol. 19, # 3 p. 332 - 336
反应条件
piperidine in toluene
Knoevenagel Condensation;
参考文献
Mao, Hui-Yu; Song, Hong; Shi, De-Qing
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 2 p. 216 - 219
反应条件
in ethanol; water; N,N-dimethyl-formamide
参考文献
Bayer Aktiengesellschaft
Patent: US4578396 A1, 1986 ;
反应条件
sodium hydride in tetrahydrofuran
参考文献
Min, Yong Ki; Asami, Tadao; Fujioka, Shozo; Murofushi, Noboru; Yamaguchi, Isomaro; Yoshida, Shigeo
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 3 p. 425 - 430