(R)-γ-Methyl-γ-butyrolactone合成路线 （共 67 条）
反应条件
hydrogenchloride; hydrogen; [RuCl2-((R)-binap)]*NEt3 in methanol T=40°C; P=2068.6 Torr; 48 h;
参考文献
King, Steven A.
Journal of Organic Chemistry, 1994 , vol. 59, # 8 p. 2253 - 2256
反应条件
trifluoroacetic acid in dichloromethane T=0 - 20°C; 6 h;
参考文献
Veeraraghavan Ramachandran; Brown, Herbert C.; Pitre, Sangeeta
Organic Letters, 2001 , vol. 3, # 1 p. 17 - 18
反应条件
hydrogen; Ru(OCOCH3)2((R)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl) in dichloromethane T=50°C; P=76000 Torr; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 60, # 2 p. 357 - 363
反应条件
1: With hydrogenchloride; 1-bromo-butane; hydrogen; [(-)-(R)-tetraMe-BITIOP]Ru(CF3COO)2 in ethanol T=45°C; P=75006 Torr; 43 h; 2: in ethanol Heating;
参考文献
Tetrahedron Asymmetry, , vol. 15, # 14 p. 2289 - 2297
反应条件
sodium hydrogencarbonate; Raney-Ni W-4 in ethanol 2 h;
参考文献
Camps, P.; Cardellach, J.; Font, J.; Ortuno, R. M.; Ponsati, O
Tetrahedron, 1982 , vol. 38, # 15 p. 2395 - 2402
反应条件
hydrogenchloride; hydrogen; (R)-1,1'-bis(diphenylphosphino)-2,2'-binapthyl; [Ru(η4-COD)(η3-methylallyl)2] in methanol; ethanol T=60°C; P=45600 - 53200 Torr; 5 h;
参考文献
Russian Chemical Bulletin, , vol. 54, # 10 p. 2374 - 2378
反应条件
hydrogen in methanol T=65°C; P=68255.5 Torr; 48 h;
参考文献
Juszkiewicz; Asztemborska; Jurczak
Polish Journal of Chemistry, 2002 , vol. 76, # 12 p. 1707 - 1711
反应条件
1: in ethanol; water 16 h; Reflux; 2: With hydrogenchloride in ethanol; water 24 h; Reflux;
参考文献
Killen, Jonathan C.; Axford, Lorraine C.; Newberry, Sarah E.; Simpson, Thomas J.; Willis, Christine L.
Organic Letters, 2012 , vol. 14, # 16 p. 4194 - 4197
反应条件
tri-n-butyl-tin hydride; sodium iodide; 2,2'-azo-bisisobutyronitrile
参考文献
Harmange, Jean-Christophe; Figadere, Bruno; Hocquemiller, Reynald
Tetrahedron: Asymmetry, 1991 , vol. 2, # 5 p. 347 - 350
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride; sodium iodide in ethylene glycol dimethyl ether 2 h; Heating;
参考文献
Bonini, Carlo; Fabio, Romano Di; Sotgiu, Giovanni; Cavagnero, Silvia
Tetrahedron, 1989 , vol. 45, # 10 p. 2895 - 2904
