(R)-γ-Methyl-γ-butyrolactone合成路线 （共 67 条）
反应条件
1: 68 percent / 220 °C / 40 Torr 2: 71 percent / pyridine / CH2Cl2 / 14 h / Ambient temperature 3: 63 percent / NaI / acetone / 8 h / Heating 4: 63 percent / CaCO3 / Ni-Ra W-4 / ethanol / 2 h View Scheme
参考文献
Tetrahedron, , vol. 38, # 15 p. 2395 - 2402
反应条件
1: 1.) THF, 12 h, reflux, 2.) 7 d 2: 68 percent / 220 °C / 40 Torr 3: 71 percent / pyridine / CH2Cl2 / 14 h / Ambient temperature 4: 63 percent / NaI / acetone / 8 h / Heating 5: 63 percent / CaCO3 / Ni-Ra W-4 / ethanol / 2 h View Scheme
参考文献
Tetrahedron, , vol. 38, # 15 p. 2395 - 2402
反应条件
1: 87 percent / 220 °C / 760 Torr 2: NaHCO3 / Raney-Ni W-4 / ethanol / 2 h View Scheme
参考文献
Tetrahedron, , vol. 39, # 3 p. 395 - 400
反应条件
1: 73 percent / 245 °C / 760 Torr 2: NaHCO3 / Raney-Ni W-4 / ethanol / 2 h View Scheme
参考文献
Tetrahedron, , vol. 39, # 3 p. 395 - 400
反应条件
1: 49 percent / 2 h / 220 °C / 760 Torr 2: NaHCO3 / Raney-Ni W-4 / ethanol / 2 h View Scheme
参考文献
Tetrahedron, , vol. 39, # 3 p. 395 - 400
反应条件
1: 83 percent / H2, K2CO3 / 10percent Pd/C / ethyl acetate / 2584 Torr / Ambient temperature 2: 87 percent / 220 °C / 760 Torr 3: NaHCO3 / Raney-Ni W-4 / ethanol / 2 h View Scheme
参考文献
Tetrahedron, , vol. 39, # 3 p. 395 - 400
反应条件
1: 100 percent / BH3*SMe2 2: 77 percent / pyridine 3: 79 percent / NaI, n-Bu3SnH / AIBN View Scheme
参考文献
Tetrahedron: Asymmetry, , vol. 2, # 5 p. 347 - 350
反应条件
1: 63 percent / NaNO2 2: 100 percent / BH3*SMe2 3: 77 percent / pyridine 4: 79 percent / NaI, n-Bu3SnH / AIBN View Scheme
参考文献
Tetrahedron: Asymmetry, , vol. 2, # 5 p. 347 - 350
反应条件
1: H2 / Pd / ethanol / ambient temperature and pressure 2: H(+) View Scheme
参考文献
Tetrahedron Letters, , vol. 21, p. 1735 - 1738
反应条件
sodium dichromate; dimethylsulfide borane complex; sulfuric acid 1.) Et2O, a) -78 to 25 deg C, b) 25 deg C, 12 h, 2.) reflux, 1 h; Yield given. Multistep reaction;
参考文献
Synthesis, , # 4 p. 311 - 313
