(R)-(-)-6-甲基-5-烯基-2-戊醇合成路线 （共 50 条）
反应条件
alcohol dehydrogenase from Thermoanaerobium brockii; NADH-specific (R)-selective-ADH; YcnD-oxidoreductase T=30°C; pH=7.5; 6 h; aq. bufferResolution of racemateEnzymatic reaction; optical yield given as percent eeenantiospecific reaction;
参考文献
Voss, Constance V.; Gruber, Christian C.; Faber, Kurt; Knaus, Tanja; Macheroux, Peter; Kroutil, Wolfgang
Journal of the American Chemical Society, 2008 , vol. 130, # 42 p. 13969 - 13972
反应条件
Candida antarctica lipase B; (η5-C5Ph5)Ru(CO)2Cl; potassium tert-butylate; sodium carbonate in tetrahydrofuran; toluene T=20°C; 72 h;
参考文献
Martin-Matute, Belen; Edin, Michaela; Bogar, Krisztian; Kaynak, F. Betuel; Baeckvall, Jan-E.
Journal of the American Chemical Society, 2005 , vol. 127, # 24 p. 8817 - 8825
反应条件
in water T=27°C; 24 h; A. niger, NaCl;
参考文献
Belan, Andre; Bolte, Jean; Fauve, Annie; Gourcy, Jean G.; Veschambre, Henri
Journal of Organic Chemistry, 1987 , vol. 52, # 2 p. 256 - 260
反应条件
Rhodococcus erythropolis DSM 43066 cells; alcohol dehydrogenase from Lactobacillus kefir; glucose dehydrogenase BS; D-glucose; nicotinamide adenine dinucleotide in alkaline aq. solution T=30°C; pH=7.5; 16 h; Title compound not separated from byproducts.;
参考文献
Angewandte Chemie - International Edition, , vol. 47, # 4 p. 741 - 745
反应条件
phosphate buffer; D-glucose; Pichia miso IAM 4682 (cells) in various solvent(s) T=30°C; 8 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Agricultural and Biological Chemistry, , vol. 54, # 6 p. 1577 - 1578
反应条件
ammonia; sodium in tetrahydrofuran
参考文献
Davies, Stephen G.; Smyth, G. Darren
Tetrahedron Asymmetry, 1996 , vol. 7, # 4 p. 1005 - 1006
参考文献
Tetrahedron Letters, , vol. 30, # 20 p. 2707 - 2708
反应条件
CAL-B in di-isopropyl ether T=30°C; Esterification; 5 h; Enzymatic reaction;
参考文献
Kita, Yasuyuki; Takebe, Yasushi; Murata, Kenji; Naka, Tadaatsu; Akai, Shuji
Journal of Organic Chemistry, 2000 , vol. 65, # 1 p. 83 - 88
反应条件
D-glucose; Yarrowia lipolytica YL10; peptone in N,N-dimethyl-formamide T=28°C; Oxidation; 72 h; Microbiological reaction; Title compound not separated from byproducts;
参考文献
Fantin, Giancarlo; Fogagnolo, Marco; Medici, Alessandro; Pedrini, Paola; Fontana, Silvia
Tetrahedron Asymmetry, 2000 , vol. 11, # 11 p. 2367 - 2373
反应条件
potassium carbonate in methanol
参考文献
Sugai, Takeshi; Ohta, Hiromichi
Agricultural and Biological Chemistry, 1990 , vol. 54, # 6 p. 1577 - 1578
