(R)-(-)-6-甲基-5-烯基-2-戊醇合成路线 （共 50 条）
反应条件
In(OSO2CF3)3 in dichloromethane T=20°C; 4 h;
参考文献
Organic Letters, , vol. 6, # 19 p. 3365 - 3367
反应条件
1: 1.) MCPBA / 1.) CHCl3, 0 deg C, 30 min, 2.) r.t., 24 h 2: 86 percent / H2 / 5percent Rh/Al2O3 / ethanol / 20 h / 20 °C / 4560 Torr 3: 47 percent / POCl3, pyridine / 20 °C 4: 56 percent / Na, NH3 / tetrahydrofuran / 1.5 h / -78 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 20 p. 2467 - 2477
反应条件
1: 86 percent / H2 / 5percent Rh/Al2O3 / ethanol / 20 h / 20 °C / 4560 Torr 2: 47 percent / POCl3, pyridine / 20 °C 3: 56 percent / Na, NH3 / tetrahydrofuran / 1.5 h / -78 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 20 p. 2467 - 2477
反应条件
1: 93 percent / tetrahydrofuran / 3 h / 20 °C 2: 1.) MCPBA / 1.) CHCl3, 0 deg C, 30 min, 2.) r.t., 24 h 3: 86 percent / H2 / 5percent Rh/Al2O3 / ethanol / 20 h / 20 °C / 4560 Torr 4: 47 percent / POCl3, pyridine / 20 °C 5: 56 percent / Na, NH3 / tetrahydrofuran / 1.5 h / -78 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 20 p. 2467 - 2477
反应条件
1: 97 percent / HCl / 1 h / 20 °C 2: 93 percent / tetrahydrofuran / 3 h / 20 °C 3: 1.) MCPBA / 1.) CHCl3, 0 deg C, 30 min, 2.) r.t., 24 h 4: 86 percent / H2 / 5percent Rh/Al2O3 / ethanol / 20 h / 20 °C / 4560 Torr 5: 47 percent / POCl3, pyridine / 20 °C 6: 56 percent / Na, NH3 / tetrahydrofuran / 1.5 h / -78 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 20 p. 2467 - 2477
反应条件
sodium hydroxide in water 23 h; lipase P30;
参考文献
Tetrahedron: Asymmetry, , vol. 1, # 7 p. 445 - 452
反应条件
sodium hydroxide; water 0.5 h;
参考文献
Arnone, Alberto; Bravo, Pierfrancesco; Panzeri, Walter; Viani, Fiorenza; Zanda, Matteo
European Journal of Organic Chemistry, 1999 , # 1 p. 117 - 127
反应条件
1: 71 percent / BuLi / tetrahydrofuran / 1.) 0 deg C, 30 min, 2.) -78 deg C, 2 h 2: 97 percent / HCl / 1 h / 20 °C 3: 93 percent / tetrahydrofuran / 3 h / 20 °C 4: 1.) MCPBA / 1.) CHCl3, 0 deg C, 30 min, 2.) r.t., 24 h 5: 86 percent / H2 / 5percent Rh/Al2O3 / ethanol / 20 h / 20 °C / 4560 Torr 6: 47 percent / POCl3, pyridine / 20 °C 7: 56 percent / Na, NH3 / tetrahydrofuran / 1.5 h / -78 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 20 p. 2467 - 2477
反应条件
1: MCPBA / CHCl3 / 3 h / 0 - 20 °C 2: 71 percent / BuLi / tetrahydrofuran / 1.) 0 deg C, 30 min, 2.) -78 deg C, 2 h 3: 97 percent / HCl / 1 h / 20 °C 4: 93 percent / tetrahydrofuran / 3 h / 20 °C 5: 1.) MCPBA / 1.) CHCl3, 0 deg C, 30 min, 2.) r.t., 24 h 6: 86 percent / H2 / 5percent Rh/Al2O3 / ethanol / 20 h / 20 °C / 4560 Torr 7: 47 percent / POCl3, pyridine / 20 °C 8: 56 percent / Na, NH3 / tetrahydrofuran / 1.5 h / -78 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 20 p. 2467 - 2477
反应条件
1: 47 percent / POCl3, pyridine / 20 °C 2: 56 percent / Na, NH3 / tetrahydrofuran / 1.5 h / -78 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 20 p. 2467 - 2477
