反应条件
1: tetrahydrofuran / 1) 5 deg C, 1 h, 2) room temperature, 1.5 h 2: 7.7 g / NaIO4 / diethyl ether; H2O / 2 h / Ambient temperature 3: 53 percent / Jones reagent / acetone / 0.25 h / 0 °C 4: 91.7 percent / H2 / Pd-C / methanol 5: 82.7 percent / 1-ethyl-3-(3-dimethylaminoproyl)carbodiimide hydrochloride / CH2Cl2 / 2 h 6: 43 percent / CF3COOH / H2O / 0.5 h / 0 °C 7: 1) 2-fluoro-1-methylpyridinium p-toluenesulfonate, 2) NaN3 / 1) CHCl3, room tempetarure, 1h, 2) HMPA, 80 deg C, 2 h 8: H2 / Pd-C View Scheme
参考文献
Bioscience, Biotechnology and Biochemistry, , vol. 60, # 3 p. 534 - 536
