反应条件
1: Fmoc-Leu-Wang resin With piperidine in N,N-dimethyl-formamide 0.5 h; solid phase reaction; 2: N-Boc-(2S,3R)-3-amino-2-hydroxy-4-phenylbutyric acid With N-ethyl-N,N-diisopropylamine; HATU in N,N-dimethyl-formamide 1 h; solid phase reaction; 3: With tri-iso-propylsilane; trifluoroacetic acid in tetrahydrofuran; water; N,N-dimethyl-formamide 2 h; solid phase reaction;
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 6 p. 1655 - 1666
