2,3,4,5-四氢-1,4-苯并硫氮杂卓合成路线 （共 5 条）
反应条件
lithium aluminium tetrahydride
参考文献
Wuensch,K.-H. et al.
Zeitschrift fuer Chemie (Stuttgart, Germany), 1967 , vol. 7, p. 185 - 186
参考文献
The Boots Company PLC
Patent: US5580866 A1, 1996 ;
反应条件
1: sulfuric acid / methanol / 18 h / 0 °C / |Inert atmosphere; |Reflux
2: sodium hydride / tetrahydrofuran; N,N-dimethyl-formamide; mineral oil / 0 - 20 °C
3: lithium aluminium tetrahydride / tetrahydrofuran / 18 h / 0 °C / |Reflux
View Scheme
参考文献
Hoffmann-La Roche Inc; Liang, Chungen; Wang, Lisha; Yun, Hongying; Zheng, Xiufang
Patent: US2013/90328 A1, 2013 ;
反应条件
1: sodium hydride / tetrahydrofuran; N,N-dimethyl-formamide; mineral oil / 0 - 20 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / 18 h / 0 °C / |Reflux
View Scheme
参考文献
Hoffmann-La Roche Inc; Liang, Chungen; Wang, Lisha; Yun, Hongying; Zheng, Xiufang
Patent: US2013/90328 A1, 2013 ;
反应条件
1: NaOEt / ethanol
2: LiAlH4
View Scheme
参考文献
Wuensch,K.-H. et al.
Zeitschrift fuer Chemie (Stuttgart, Germany), 1967 , vol. 7, p. 185 - 186
