(R)-(-)-2-(4-甲氧基苯基)-1-甲基乙胺合成路线 (共 17 条)
反应条件
water; potassium hydroxide Reflux; optical yield given as percent ee;
参考文献
Munoz, Lourdes; Rodriguez, Anna M.; Rosell, Gloria; Bosch, M. Pilar; Guerrero, Angel
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 23 p. 8171 - 8177
反应条件
ammonia; water in dichloromethane Product distribution / selectivity;
参考文献
WO2008/104781 A1, ;
Page/Page column 42; 45 ;
反应条件
1: 78 percent / LiAlH4 / diethyl ether / 2 h / Heating 2: Candida antarctica lipase B 3: 3M aq. KOH / Heating View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 11, # 13 p. 2705 - 2717
反应条件
Candida antartica lipase B; triethylamine T=35°C; Inert atmosphereEnzymatic reaction; optical yield given as percent ee;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 23 p. 8171 - 8177
反应条件
potassium hydroxide Hydrolysis; Heating;
参考文献
Tetrahedron Asymmetry, , vol. 11, # 13 p. 2705 - 2717
反应条件
water; potassium hydroxide Reflux; optical yield given as percent ee;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 23 p. 8171 - 8177
反应条件
4-(N,N-dimethlyamino)pyridine
参考文献
Koszelewski, Dominik; Lavandera, Ivan; Clay, Dorina; Rozzell, David; Kroutil, Wolfgang
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 17 p. 2761 - 2766