1: 64 percent / phosphorus pentachloride / 72 h / 115 °C 2: 80 percent / tetrahydrofuran-d8 / 48 h / Ambient temperature; in a dry box 3: 60 percent / sodium / 4 h / Heating 4: concentrated aq. HCl / tetrahydrofuran / 0.08 h View Scheme
参考文献
Dainter, Ronald S.; Jackson, Tracey; Omar, Abdirahman H. H.; Suschitzky, Hans; Wakefield, Basil J.; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 283 - 287
1.1: carbonyldiimidazole / tetrahydrofuran / 2.5 h / 0 - 20 °C 1.2: tetrahydrofuran / 0.25 h / -78 °C 2.1: NaH / tetrahydrofuran / 0.17 h / 0 °C 2.2: tetrahydrofuran / 8 h / 0 °C 3.1: p-toluenesufonic acid monohydrate / toluene / 20 h / 80 °C View Scheme
参考文献
Imoto, Hiroshi; Sugiyama, Yasuo; Kimura, Hiroyuki; Momose, Yu
Chemical and Pharmaceutical Bulletin, 2003 , vol. 51, # 2 p. 138 - 151