4,4-二甲基-2-戊酮合成路线 （共 111 条）
反应条件
1: diethyl ether 2: naphthalene-sulfonic acid-(2) / Erhitzen des enststehenden Gemisches von 2.2.4-Trimethyl-hexen-(4),2.2-Dimethyl-4-methylen-hexan und 2.2.4-Trimethyl-hexen-(3) an Nickel-Kieselgur View Scheme
参考文献
Howard et al.
Journal of Research of the National Bureau of Standards (United States), 1947 , vol. 38, p. 391
Chem. Zentralbl., 1947 , vol. 118, p. 5291
反应条件
2: (i) MeI, (ii) /BRN= 4725512/
3: (i) (hydrolysis), (ii) (decarboxylation)
4: NaH
View Scheme
参考文献
Newkome,G.R. et al.
Journal of the Chemical Society, Chemical Communications, 1972 , p. 905 - 906
反应条件
1: dioxane; diethyl ether; bromine
2: diethyl ether
3: lithium alanate; diethyl ether
View Scheme
参考文献
Sarel; Newman
Journal of the American Chemical Society, 1956 , vol. 78, p. 5416,5418
反应条件
2: HCO2H
View Scheme
参考文献
Yvernault,T.; Mazet,M.
Bulletin de la Societe Chimique de France, 1971 , # 7 p. 2652 - 2656
参考文献
Wiberg,K.B.; Squires,R.R.
Journal of the American Chemical Society, 1979 , vol. 101, p. 5512 - 5515
反应条件
1: sulfuric acid
2: boron fluoride / beim Erhitzen des Reaktionsgemisches mit wss. Natriumacetat-Loesung
View Scheme
参考文献
Man et al.
Journal of the American Chemical Society, 1952 , vol. 74, p. 3228
反应条件
(i) BF3, (ii) aq. NaOAc; Multistep reaction;
参考文献
Mao,C.-L. et al.
Journal of Organic Chemistry, 1969 , vol. 34, # 5 p. 1425 - 1429
反应条件
1: ammonia
2: aqueous sulfuric acid; mercury (II)-sulfate
3: diethyl ether
4: sulfuric acid
5: lithium alanate; diethyl ether
View Scheme
参考文献
Hickinbottom et al.
Journal of the Chemical Society, 1954 , p. 2529,2531
反应条件
1: NaOBr
2: SOCl2
3: bromine
View Scheme
参考文献
Homeyer; Whitmore; Wallingford
Journal of the American Chemical Society, 1933 , vol. 55, p. 4209,4212
参考文献
Abbot,E.M.; Bellamy,A.J.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1978 , p. 254 - 258
