2-氨基-5-溴-3-甲氧基吡嗪合成路线 （共 6 条）
反应条件
in methanol Heating;
参考文献
Jiang, Biao; Yang, Cai-Guang; Xiong, Wen-Nan; Wang, Jun
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 5 p. 1149 - 1154
反应条件
N-bromosuccinmide in dichloromethane T=0 - 20°C; 2.75 h; Inert atmosphere;
参考文献
MedChemComm, , vol. 5, # 3 p. 333 - 337
反应条件
in methanol 16 h; Ambient temperature;
参考文献
Barlin
Australian Journal of Chemistry, 1983 , vol. 36, # 5 p. 983 - 992
反应条件
1: With hydrogen bromide in water T=20°C; 1 h; 2: With sodium nitrite in water 0.333333 h; Cooling; Further stages.;
参考文献
Yang, Cai-Guang; Liu, Gang; Jiang, Biao
Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9392 - 9396
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in methanol; benzene
Suzuki coupling; Heating;
参考文献
Yang, Cai-Guang; Liu, Gang; Jiang, Biao
Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9392 - 9396
反应条件
hydrogen iodide; sodium nitrite in water; acetonitrile
T=50°C; 30 h;
参考文献
Garg, Neil K.; Sarpong, Richmond; Stoltz, Brian M.
Journal of the American Chemical Society, 2002 , vol. 124, # 44 p. 13179 - 13184
