4-羟甲基苯硼酸合成路线

参考文献

Spicer, Julie A.; Lena, Gersande; Lyons, Dani M.; Huttunen, Kristiina M.; Miller, Christian K.; O'Connor, Patrick D.; Bull, Matthew; Helsby, Nuala; Jamieson, Stephen M. F.; Denny, William A.; Ciccone, Annette; Browne, Kylie A.; Lopez, Jamie A.; Rudd-Schmidt, Jesse; Voskoboinik, Ilia; Trapani, Joseph A.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9542 - 9555

34598-49-75-溴茚酮+

59016-93-24-羟甲基苯硼酸

848760-74-74-(1H-吲哚-4-基)苯甲醛

参考文献

Panarello, Anthony P.; Vassylyev, Oleksiy; Khinast, Johannes G.
Tetrahedron Letters, 2005 , vol. 46, # 8 p. 1353 - 1356

5332-24-13-溴喹啉+

59016-93-24-羟甲基苯硼酸

893739-01-0[4-(2,3-二氢-1,4-苯并二氧杂环己-6-基)苯基]甲醇

参考文献

Holzer, Marcel; Ziegler, Sigrid; Neugebauer, Alexander; Kronenberger, Bernd; Klein, Christian D.; Hartmann, Rolf W.
Archiv der Pharmazie, 2008 , vol. 341, # 8 p. 478 - 484

59016-93-24-羟甲基苯硼酸+

29682-15-35-溴吡啶-2-羧酸甲酯

927435-98-1

参考文献

IRM LLC
Patent: WO2007/24922 A1, 2007 ;
Location in patent: Page/Page column 22-23 ;
WO 2007/024922 A1

20826-04-45-溴烟酸+

59016-93-24-羟甲基苯硼酸

928148-47-4

参考文献

GLAXO GROUP LIMITED
Patent: WO2007/25774 A2, 2007 ;
Location in patent: Page/Page column 45 ;
WO 2007/025774 A2

5326-23-86-氯烟酸+

59016-93-24-羟甲基苯硼酸

928166-93-2

参考文献

Coteron, Jose M.; Catterick, David; Castro, Julia; Chaparro, Maria J.; Diaz, Beatriz; Fernandez, Esther; Ferrer, Santiago; Gamo, Francisco J.; Gordo, Mariola; Gut, Jiri; De Las Heras, Laura; Legac, Jennifer; Marco, Maria; Miguel, Juan; Munoz, Vicente; Porras, Esther; De La Rosa, Juan C.; Ruiz, Jose R.; Sandoval, Elena; Ventosa, Pilar; Rosenthal, Philip J.; Fiandor, Jose M.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 16 p. 6129 - 6152

1899-24-75-溴-2-呋喃甲醛+

59016-93-24-羟甲基苯硼酸

603986-80-7

参考文献

Pfefferkorn, Jeffrey A.; Greene, Meredith L.; Nugent, Richard A.; Gross, Rebecca J.; Mitchell, Mark A.; Finzel, Barry C.; Harris, Melissa S.; Wells, Peter A.; Shelly, John A.; Anstadt, Robert A.; Kilkuskie, Robert E.; Kopta, Laurice A.; Schwende, Francis J.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 10 p. 2481 - 2486

14508-49-72-氯吡嗪+

59016-93-24-羟甲基苯硼酸

545421-49-6[4-(2-吡嗪基)苯基]甲醇

参考文献

ARENA PHARMACEUTICALS, INC.; JONES, Robert M.; BUZARD, DAniel J.; HAN, Sangdon; KIM, Sun He; LEHMANN, Juerg; ULLMAN, Brett; MOODY, Jeanne V.; ZHU, Xiuwen; STIRN, Scott
Patent: WO2010/11316 A1, 2010 ;
Location in patent: Page/Page column 76-77 ;
WO 2010/011316 A1

59016-93-24-羟甲基苯硼酸+

540-37-4对碘苯胺

393522-98-0

参考文献

Maity, Indrajit; Rasale, Dnyaneshwar B.; Das, Apurba K.
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