4-烯丙基-5-(2-环己基乙基)-4H-1,2,4-噻唑-3-硫醇合成路线 （共 4 条）
反应条件
sodium hydroxide in water
2 h; Reflux;
参考文献
Gobis, Katarzyna; Foks, Henryk; Bojanowski, Krzysztof; Augustynowicz-Kopec, Ewa; Napiorkowska, Agnieszka
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 1 p. 137 - 144
反应条件
1: thionyl chloride / 3 h / Reflux
2: hydrazine hydrate / methanol; water / 3 h / Reflux
3: methanol / Reflux
4: sodium hydroxide / water / 2 h / Reflux
View Scheme
参考文献
Gobis, Katarzyna; Foks, Henryk; Bojanowski, Krzysztof; Augustynowicz-Kopec, Ewa; Napiorkowska, Agnieszka
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 1 p. 137 - 144
反应条件
1: hydrazine hydrate / methanol; water / 3 h / Reflux
2: methanol / Reflux
3: sodium hydroxide / water / 2 h / Reflux
View Scheme
参考文献
Gobis, Katarzyna; Foks, Henryk; Bojanowski, Krzysztof; Augustynowicz-Kopec, Ewa; Napiorkowska, Agnieszka
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 1 p. 137 - 144
反应条件
1: methanol / Reflux
2: sodium hydroxide / water / 2 h / Reflux
View Scheme
参考文献
Gobis, Katarzyna; Foks, Henryk; Bojanowski, Krzysztof; Augustynowicz-Kopec, Ewa; Napiorkowska, Agnieszka
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 1 p. 137 - 144
