4-溴-2-甲基-2H-吲唑合成路线 (共 3 条)
反应条件
in ethyl acetate T=20°C;
参考文献
Takeda Pharmaceutical Company Limited
Patent: EP2141150 A1, 2010 ;
Location in patent: Page/Page column 63-64 ;
反应条件
potassium carbonate in acetone Reflux;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 20, # 17 p. 5296 - 5304
反应条件
1.1: tetrafluoroboric acid; sodium nitrite / water / 3 h / 0 - 20 °C 1.2: 2 h / 20 °C 2.1: potassium carbonate / acetone / |Reflux View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 20, # 17 p. 5296 - 5304