1-甲基-2-[(E)-2-苯基乙烯基]-1H-苯并咪唑合成路线 （共 17 条）
反应条件
potassium hydroxide T=220°C; 0.5 h;
参考文献
Chemistry of Heterocyclic Compounds, , vol. 33, # 8 p. 949 - 953
反应条件
N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate in acetone
T=20°C; 3 h;
参考文献
Ramaiah; Dubey; Eswara Rao; Ramanatham; Kumar; Grossert; Hooper
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000 , vol. 39, # 12 p. 904 - 914
反应条件
1: N-methyl-para-phenylenediamine With trimethylaluminum chloride in toluene
T=0 - 20°C;
2: hydroxymethyl JandaJelTM resin-bound styryl ester in toluene
24 h; Heating; Further stages.;
参考文献
Matsushita, Hana; Lee, Sang-Hyeup; Joung, Meyoungju; Clapham, Bruce; Janda, Kim D.
Tetrahedron Letters, 2004 , vol. 45, # 2 p. 313 - 316
反应条件
sodium hydroxide in acetone
1 h;
参考文献
Popov
Chemistry of Heterocyclic Compounds, 1997 , vol. 33, # 8 p. 949 - 953
反应条件
copper(l) iodide; palladium diacetate; lithium tert-butylate in 1,4-dioxane
T=120°C; 0.5 h; Microwave irradiationInert atmosphere; regioselective reaction;
参考文献
Vabre, Roxane; Chevot, Franciane; Legraverend, Michel; Piguel, Sandrine
Journal of Organic Chemistry, 2011 , vol. 76, # 22 p. 9542 - 9547
反应条件
1,10-phenanthroline; palladium (II) trifluoroacetate; silver trifluoroacetate in toluene
T=130°C; 16 h;
参考文献
Lee, Wei-Chih; Wang, Ting-Hsuan; Ong, Tiow-Gan
Chemical Communications, 2014 , vol. 50, # 28 p. 3671 - 3673
反应条件
hydrogenchloride; manganese(IV) oxide; 4 A molecular sieve in diethyl ether; toluene
T=105°C; 18 h;
参考文献
Wilfred, Cecilia D.; Taylor, Richard J. K.
Synlett, 2004 , # 9 p. 1628 - 1630
反应条件
1: 24 h / 180 °C
2: K2CO3 / dimethylformamide / 3 h / 20 °C
View Scheme
参考文献
Petzer, Jacobus P.; Steyn, Salome; Castagnoli, Kay P.; Chen, Jiang-Fan; Schwarzschild, Michael A.; Van Der Schyf, Cornelis J.; Castagnoli, Neal
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 7 p. 1299 - 1310
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=0 - 20°C;
参考文献
van den Berg, Deidre; Zoellner, Kevin R.; Ogunrombi, Modupe O.; Malan, Sarel F.; Terre'Blanche, Gisella; Castagnoli Jr., Neal; Bergh, Jacobus J.; Petzer, Jacobus P.
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 11 p. 3692 - 3702
反应条件
1,10-phenanthroline; palladium (II) trifluoroacetate; silver trifluoroacetate in toluene
T=130°C; 16 h;
参考文献
Lee, Wei-Chih; Wang, Ting-Hsuan; Ong, Tiow-Gan
Chemical Communications, 2014 , vol. 50, # 28 p. 3671 - 3673
