反应条件
1.1: triethylamine; tris-(dibenzylideneacetone)dipalladium(0); 1,1'-bis-(diphenylphosphino)ferrocene / N,N-dimethyl-formamide / 0.17 h / 20 °C / |Inert atmosphere 1.2: 1.5 h / 60 °C / |Inert atmosphere 2.1: sodium hydroxide / ethanol / 15 h / 20 °C 3.1: sulfuric acid / 96 h / 20 °C View Scheme
参考文献
Procopiou, Panayiotis A.; Barrett, Victoria J.; Biggadike, Keith; Butchers, Peter R.; Craven, Andrew; Ford, Alison J.; Guntrip, Stephen B.; Holmes, Duncan S.; Hughes, Sara C.; Jones, Anne E.; Looker, Brian E.; Mutch, Peter J.; Ruston, Mark; Needham, Deborah; Smith, Claire E.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 1 p. 159 - 170