间溴苯酚合成路线

参考文献

Simonetti, Sebastian O.; Larghi, Enrique L.; Bracca, Andrea B. J.; Kaufman, Teodoro S.
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 20 p. 4124 - 4134

591-20-8间溴苯酚

93703-48-13,3’,4,4’-四溴联苯醚

参考文献

Marsh, Goeran; Hu, Jiwei; Jakobsson, Eva; Rahm, Sara; Bergman, Aeke
Environmental Science and Technology, 1999 , vol. 33, # 17 p. 3033 - 3037

591-20-8间溴苯酚

40248-84-83-羟基苯硫酚

参考文献

Zhang, Mingbao; Ryckman, David; Chen, Guohua; MacMillan, Eric; Duquette, Jason
Synthesis, 2003 , # 1 p. 112 - 116

591-20-8间溴苯酚

20759-40-43-羟基苯磺酰胺

参考文献

Selnick; Bourgeois; Butcher; Radzilowski
Tetrahedron Letters, 1993 , vol. 34, # 13 p. 2043 - 2046

108-01-0N,N-二甲基乙醇胺+

591-20-8间溴苯酚

221915-84-02-(3-溴苯氧基)-N,N-二甲基乙胺

参考文献

ARRAY BIOPHARMA INC.; GENENTECH, INC.; AHRENDT, Kateri A.; BUCKMELTER, Alexandre J.; DE MEESE, Jason; GRINA, Jonas; HANSEN, Joshua D.; LAIRD, Ellen R.; LUNGHOFER, Paul; MORENO, David; NEWHOUSE, Brad; REN, Li; SEO, Jeongbeob; TIAN, Hongqi; WENGLOWSKY, Steven Mark; FENG, Bainian; GUNZNER, Janet; MALESKY, Kim; MATHIEU, Simon; RUDOLPH, Joachim; WEN, Zhaoyang; YOUNG, Wendy B.
Patent: WO2009/111279 A1, 2009 ;
Location in patent: Page/Page column 93 ;
WO 2009/111279 A1

591-20-8间溴苯酚+

107-99-32-氯-N,N-二甲基乙胺

221915-84-02-(3-溴苯氧基)-N,N-二甲基乙胺

参考文献

NOVARTIS AG
Patent: WO2009/87212 A2, 2009 ;
Location in patent: Page/Page column 114 ;

591-20-8间溴苯酚+

107-99-32-氯-N,N-二甲基乙胺

221915-84-02-(3-溴苯氧基)-N,N-二甲基乙胺+

2474-07-92-(4-溴苯氧基)-N,N-二甲基乙胺

参考文献

Bristol-Myers Squibb Company
Patent: US6255496 B1, 2001 ;

591-20-8间溴苯酚+

4584-46-7二甲氨基氯乙烷盐酸

221915-84-02-(3-溴苯氧基)-N,N-二甲基乙胺

参考文献

Duffey, Matthew O.; Vos, Tricia J.; Adams, Ruth; Alley, Jennifer; Anthony, Justin; Barrett, Cynthia; Bharathan, Indu; Bowman, Douglas; Bump, Nancy J.; Chau, Ryan; Cullis, Courtney; Driscoll, Denise L.; Elder, Amy; Forsyth, Nancy; Frazer, Jonathan; Guo, Jianping; Guo, Luyi; Hyer, Marc L.; Janowick, David; Kulkarni, Bheemashankar; Lai, Su-Jen; Lasky, Kerri; Li, Gang; Li, Jing; Liao, Debra; Little, Jeremy; Peng, Bo; Qian, Mark G.; Reynolds, Dominic J.; Rezaei, Mansoureh; Scott, Margaret Porter; Sells, Todd B.; Shinde, Vaishali; Shi, Qiuju Judy; Sintchak, Michael D.; Soucy, Francois; Sprott, Kevin T.; Stroud, Stephen G.; Nestor, Michelle; Visiers, Irache; Weatherhead, Gabriel; Ye, Yingchun; Damore, Natalie
Journal of Medicinal Chemistry, 2012 , vol. 55, # 1 p. 197 - 208

591-20-8间溴苯酚+

123855-51-6N-Boc-4-哌啶甲醇

180847-24-9

参考文献

KADMON CORPORATION, LLC; BOXER, Michael; RYAN, John; TONRA, James
Patent: WO2014/55999 A2, 2014 ;
Location in patent: Paragraph 0234 ;

57-57-8β-丙内酯+

591-20-8间溴苯酚

18386-03-3

参考文献

Mochida Pharmaceutical Co., Ltd.
Patent: EP2518064 A1, 2012 ;
Location in patent: Page/Page column 42 ;