反应条件
1: piperidine; pyridine / 12 h / 80 °C / |Inert atmosphere
2: palladium 10 on activated carbon; hydrogen / methanol
3: polyphosphoric acid / 4 h / 80 °C / |Inert atmosphere
4: hydrogen bromide; acetic acid / water / 2 h / 110 °C / |Inert atmosphere
5: potassium carbonate / acetone / 5 h / |Reflux; |Inert atmosphere
View Scheme
参考文献
Nagarapu, Lingaiah; Vulupala, Hanmanth Reddy; Bantu, Rajashaker; Sajja, Yashodakrishna; Nanubolu, Jagadeesh Babu
Tetrahedron Asymmetry, 2014 , vol. 25, # 6-7 p. 578 - 582