4,6-二氯-7-氮杂吲哚合成路线 （共 3 条）
反应条件
methanesulfonyl chloride in N,N-dimethyl-formamide T=80°C; 3 h;
参考文献
L'Heureux, Alexandre; Thibault, Carl; Ruel, Rejean
Tetrahedron Letters, 2004 , vol. 45, # 11 p. 2317 - 2319
反应条件
1: m-chloroperbenzoic acid / CHCl3 / 1 h / 0 °C 2: 58 percent / methanesulfonyl chloride / dimethylformamide / 3 h / 80 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 45, # 11 p. 2317 - 2319
反应条件
1.1: 62 percent / NaH / tetrahydrofuran / 1 h
2.1: 88 percent / K2CO3 / dimethylsulfoxide / 2 h / 100 °C
3.1: 92 percent / H2 / Pd/C / ethanol / 24 h / 20 °C
4.1: TFA / CH2Cl2 / 2 h / 20 °C
4.2: 79 percent / AcONa / ethanol / 1 h
View Scheme
参考文献
Figueroa-Perez, Santiago; Bennabi, Samir; Schirok, Hartmut; Thutewohl, Michael
Tetrahedron Letters, 2006 , vol. 47, # 13 p. 2069 - 2072
