(1-氧代-1H-异喹啉-2-基)-乙酸合成路线 （共 5 条）
反应条件
trifluoroacetic acid in dichloromethane
T=20°C; Cooling;
参考文献
ARES TRADING S.A.; SWINNEN, Dominique; MORANDI, Federica
Patent: WO2013/92979 A1, 2013 ;
Location in patent: Page/Page column 54; 55 ;
反应条件
1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 20 °C
2: trichlorophosphate / 105 °C / |Cooling with ice
3: acetic acid; ammonium acetate / 3 h / 100 °C
4: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C
5: trifluoroacetic acid / dichloromethane / 20 °C / |Cooling
View Scheme
参考文献
ARES TRADING S.A.; SWINNEN, Dominique; MORANDI, Federica
Patent: WO2013/92979 A1, 2013 ;
反应条件
1: trichlorophosphate / 105 °C / |Cooling with ice
2: acetic acid; ammonium acetate / 3 h / 100 °C
3: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C
4: trifluoroacetic acid / dichloromethane / 20 °C / |Cooling
View Scheme
参考文献
ARES TRADING S.A.; SWINNEN, Dominique; MORANDI, Federica
Patent: WO2013/92979 A1, 2013 ;
反应条件
1: acetic acid; ammonium acetate / 3 h / 100 °C
2: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C
3: trifluoroacetic acid / dichloromethane / 20 °C / |Cooling
View Scheme
参考文献
ARES TRADING S.A.; SWINNEN, Dominique; MORANDI, Federica
Patent: WO2013/92979 A1, 2013 ;
反应条件
1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C
2: trifluoroacetic acid / dichloromethane / 20 °C / |Cooling
View Scheme
参考文献
ARES TRADING S.A.; SWINNEN, Dominique; MORANDI, Federica
Patent: WO2013/92979 A1, 2013 ;
