2-苯基噁唑-4-羧酸甲酯合成路线 （共 28 条）
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in benzene
T=80°C; 2 h;
参考文献
Meyers; Tavares, Francis X.
Journal of Organic Chemistry, 1996 , vol. 61, # 23 p. 8207 - 8215
反应条件
1: With potassium carbonate in N,N-dimethyl acetamide
T=20°C; 12 h;
2: With trichloromonobromomethane; 1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl acetamide
T=0 - 20°C; 12 h;
参考文献
Graham, Thomas H.
Organic Letters, 2010 , vol. 12, # 16 p. 3614 - 3617
反应条件
manganese(IV) oxide in benzene
22 h; Heating;
参考文献
Aoyama, Toyohiko; Sonoda, Naoko; Yamauchi, Mariko; Toriyama, Kyoko; Anzai, Masahiro; Ando, Akira; Shioiri, Takayuki
Synlett, 1998 , # 1 p. 35 - 36
反应条件
1: PPh3; CCl4; i-Pr2NEt / acetonitrile; CH2Cl2 / 0 - 20 °C
2: CuBr; DBU; HMTA / CH2Cl2
View Scheme
参考文献
Zylstra, Eric J.; She, Miles W.-L.; Salamant, Walter A.; Leahy, James W.
Synlett, 2007 , # 4 p. 623 - 627
反应条件
1: With magnesium sulfate; triethylamine in tetrahydrofuran
T=20°C; 12 h;
2: With trichloromonobromomethane; 1,8-diazabicyclo[5.4.0]undec-7-ene in dichloromethane
T=0 - 20°C; 12 h;
参考文献
Graham, Thomas H.
Organic Letters, 2010 , vol. 12, # 16 p. 3614 - 3617
反应条件
tert.-butylhydroperoxide; potassium carbonate; copper dichloride in acetonitrile
参考文献
Yamamoto, Kana; Chen, Ye Grace; Buono, Frederic G.
Organic Letters, 2005 , vol. 7, # 21 p. 4673 - 4676
反应条件
1: 100 percent / pyridine / 1 h / Ambient temperature
2: 1.) NCS, 2.) EtN(i-Pr)2 / 1.) DMF, r.t., 1 h
3: NaOMe / methanol / 1 h / Ambient temperature
View Scheme
参考文献
Shapiro, Rafael
Journal of Organic Chemistry, 1993 , vol. 58, # 21 p. 5759 - 5764
反应条件
1: 1.) NCS, 2.) EtN(i-Pr)2 / 1.) DMF, r.t., 1 h
2: NaOMe / methanol / 1 h / Ambient temperature
View Scheme
参考文献
Shapiro, Rafael
Journal of Organic Chemistry, 1993 , vol. 58, # 21 p. 5759 - 5764
反应条件
sodium methylate in methanol
1 h; Ambient temperature; Yield given;
参考文献
Shapiro, Rafael
Journal of Organic Chemistry, 1993 , vol. 58, # 21 p. 5759 - 5764
反应条件
1: CH2Cl2 / 24 h / Ambient temperature
2: 83 percent / benzoyl peroxide, NBS / benzene / 2 h / Heating
View Scheme
参考文献
Meyers; Tavares, Francis X.
Journal of Organic Chemistry, 1996 , vol. 61, # 23 p. 8207 - 8215
