2-(4-氨基-3,5-二甲基-吡唑-1-基)-乙醇合成路线 （共 2 条）
反应条件
hydrogen; platinum(IV) oxide in ethanol; ethyl acetate
T=20°C; 30 h;
参考文献
ACTELION PHARMACEUTICALS LTD; BOLLI, Martin; BOSS, Christoph; BROTSCHI, Christine; GUDE, Markus; HEIDMANN, Bibia; SIFFERLEN, Thierry; WILLIAMS, Jodi, T.
Patent: WO2012/110986 A1, 2012 ;
Location in patent: Page/Page column 58 ;
WO 2012/110986 A1
反应条件
1: caesium carbonate / acetonitrile / 3 h / 90 °C / Reflux
2: hydrogen / platinum(IV) oxide / ethyl acetate; ethanol / 30 h / 20 °C
View Scheme
参考文献
ACTELION PHARMACEUTICALS LTD; BOLLI, Martin; BOSS, Christoph; BROTSCHI, Christine; GUDE, Markus; HEIDMANN, Bibia; SIFFERLEN, Thierry; WILLIAMS, Jodi, T.
Patent: WO2012/110986 A1, 2012 ;
WO 2012/110986 A1
