6-甲氧基-5-硝基烟酸甲酯合成路线 （共 6 条）
反应条件
palladium on carbon in methyl 6-methylthio-5-nitronicotinate; ethyl acetate
参考文献
RHONE-POULENC RORER LIMITED
Patent: EP741707 B1, 1998 ;
参考文献
Almirall, S.A.
Patent: EP2527344 A1, 2012 ;
Location in patent: Page/Page column 24 ;
EP 2527344 A1
反应条件
sodium methylate in methanol; water
参考文献
Aventis Pharma Limited
Patent: US6472412 B1, 2002 ;
反应条件
sodium methylate in methanol; water; sodium thiomethoxide
参考文献
RHONE-POULENC RORER LIMITED
Patent: EP741707 B1, 1998 ;
反应条件
1.1: N,N-dimethyl-formamide; thionyl chloride / 60 - 80 °C
1.2: 0 °C
2.1: methanol
View Scheme
参考文献
Almirall, S.A.
Patent: EP2527344 A1, 2012 ;
EP 2527344 A1
反应条件
palladium on carbon in methyl 6-methylthio-5-nitronicotinate; ethyl acetate
参考文献
RHONE-POULENC RORER LIMITED
Patent: EP741707 B1, 1998 ;
