3-硝基-4-甲氧基苄基磺酰基乙酸合成路线 （共 7 条）
反应条件
dihydrogen peroxide in acetic acid T=50°C; 6 h; chemoselective reaction;
参考文献
Chahrour, Osama; Abdalla, Ashraf; Lam, Frankie; Midgley, Carol; Wang, Shudong
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 10 p. 3066 - 3069
反应条件
dihydrogen peroxide in acetic acid
参考文献
TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
Patent: US2010/305059 A1, 2010 ;
反应条件
1: sodium carbonate / methanol / 1 h / Reflux 2: dihydrogen peroxide / acetic acid / 6 h / 50 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 10 p. 3066 - 3069
反应条件
1: N-bromosuccinmide; dibenzoyl peroxide / tetrachloromethane / 18 h / Inert atmosphere; Reflux 2: sodium hydroxide / methanol / 3 h / 20 °C / Inert atmosphere 3: dihydrogen peroxide; acetic acid / water / 24 h / 20 °C / Inert atmosphere View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 18 p. 6254 - 6276
反应条件
1: phosphorus tribromide / toluene / 0.5 h / 40 - 100 °C / Inert atmosphere 2: sodium hydroxide / methanol / 3 h / 20 °C / Inert atmosphere 3: dihydrogen peroxide; acetic acid / water / 24 h / 20 °C / Inert atmosphere View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 18 p. 6254 - 6276
反应条件
1: sodium tetrahydroborate / methanol / 1 h / 0 - 5 °C / Inert atmosphere 2: phosphorus tribromide / toluene / 0.5 h / 40 - 100 °C / Inert atmosphere 3: sodium hydroxide / methanol / 3 h / 20 °C / Inert atmosphere 4: dihydrogen peroxide; acetic acid / water / 24 h / 20 °C / Inert atmosphere View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 18 p. 6254 - 6276
反应条件
1: piperidine / pyridine / 36 h / 20 °C
3: sodium acetate
4: water; sodium carbonate
View Scheme
参考文献
Reddy, M. V. Ramana; Venkatapuram, Padmavathi; Mallireddigari, Muralidhar R.; Pallela, Venkat R.; Cosenza, Stephen C.; Robell, Kimberly A.; Akula, Balaiah; Hoffman, Benjamin S.; Reddy, E. Premkumar
Journal of Medicinal Chemistry, 2011 , vol. 54, # 18 p. 6254 - 6276
