9-(2-羟基-3-壬基)腺嘌呤合成路线 （共 2 条）
反应条件
1: 50 percent / Me3SiBr, DMSO / acetonitrile / 2 h / Ambient temperature
2: 55 percent / K2CO3 / N,N-dimethyl-acetamide / 0.5 h / 70 °C
3: 100 percent / aq. NaBH4 / ethanol / 1.5 h / Ambient temperature
View Scheme
参考文献
Zhao, Yong-Zhong; Van Breemen, Richard B.; Nikolic, Dejan; Huang, Chao-Ran; Woodbury, Charles P.; Schilling, Alexander; Venton, Duane L.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 25 p. 4006 - 4012
反应条件
1: 55 percent / K2CO3 / N,N-dimethyl-acetamide / 0.5 h / 70 °C
2: 100 percent / aq. NaBH4 / ethanol / 1.5 h / Ambient temperature
View Scheme
参考文献
Zhao, Yong-Zhong; Van Breemen, Richard B.; Nikolic, Dejan; Huang, Chao-Ran; Woodbury, Charles P.; Schilling, Alexander; Venton, Duane L.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 25 p. 4006 - 4012
