THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; HE, Biao; MANN, Michael; JABLONS, David, M.
Patent: WO2013/13190 A1, 2013 ;
Location in patent: Paragraph 00216 ;
1: dimethyl methoxycarbonylmethanephosphonate With sodium hydride in N,N-dimethyl-formamide T=0°C; 0.333333 h; 2: tert-butyl 4-oxo-piperidine-1-carboxylate in N,N-dimethyl-formamide T=0 - 20°C; 3.33333 h;
参考文献
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; THE CURATORS OF THE UNIVERSITY OF MISSOURI; GINSBURG, David; LARSEN, Scott D.; YESTREPSKY, Bryan; SUN, Hongmin
Patent: WO2013/166282 A2, 2013 ;
Location in patent: Page/Page column 95 ;
1: dimethyl methoxycarbonylmethanephosphonate With sodium hydride in N,N-dimethyl-formamide T=20°C; 2: 2‐chloro-5‐methylnicotinaldehyde in N,N-dimethyl-formamide T=20°C; Horner-Wadsworth-Emmons olefination;
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18-crown-6 and KN(TMS)2 in tetrahydrofuran; toluene
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参考文献
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sodium hydride in N,N-dimethyl-formamide
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