1: With n-butyllithium; tetra(o-fluorophenyl)-TADDOL in tetrahydrofuran; hexane T=0 - 25°C; 0.5 h; 2: With hydrogenchloride in methanol T=25°C; 0.166667 h; Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 126, # 10 p. 3070 - 3071
sodium hypochlorite; 4-phenylpyridine-N-oxide; (R,R)-(-)-(salen)Mn(III) chloride in phosphate buffer; dichloromethane T=0°C; pH=11; 18 h; Title compound not separated from byproducts;
1: With sodium hypochlorite; 4-phenylpyridine-N-oxide; phosphate buffer; (S,S)-Jacobsen’s catalyst in dichloromethane T=-10 - 0°C; pH=11; 18 h; 2: With trifluoroacetic acid in diethyl ether; water T=0°C; Title compound not separated from byproducts;
