5-甲氧基-3-吲哚甲酸乙酯合成路线 （共 7 条）
反应条件
pyrrolidine in toluene T=20°C; Inert atmosphere;
参考文献
Huehls, C. Bryan; Hood, Tyler S.; Yang, Jiong
Angewandte Chemie - International Edition, 2012 , vol. 51, # 21 p. 5110 - 5113
反应条件
sulfuric acid 20 h; Reflux;
参考文献
European Journal of Medicinal Chemistry, , vol. 55, p. 432 - 438
反应条件
1: 75 percent / HBF4*OEt2 / CH2Cl2 / -78 °C 2: 62 percent / H2 / Pd/C / methanol / 24 h / 20 °C / 2280 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 71, # 12 p. 4675 - 4677
反应条件
1: 78 percent / benzoquinone, lithium chloride / dichlorobis(acetonitrile)palladium(II) / tetrahydrofuran / 24 h / Ambient temperature 2: 82 percent / triethylamine / palladium(II) acetate, tri-o-tolylphosphine / acetonitrile / 20 h / 100 °C View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 59, # 3 p. 927 - 928
反应条件
1: 78 percent / benzoquinone, lithium chloride / dichlorobis(acetonitrile)palladium(II) / tetrahydrofuran / 24 h / Ambient temperature 2: 82 percent / triethylamine / palladium(II) acetate, tri-o-tolylphosphine / acetonitrile / 20 h / 100 °C View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 59, # 3 p. 927 - 928
反应条件
1: tetrahydrofuran / 0.25 h / -78 °C / Inert atmosphere 2: toluene / 80 °C / Inert atmosphere 3: pyrrolidine / toluene / 20 °C / Inert atmosphere View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 51, # 21 p. 5110 - 5113
反应条件
1: toluene / 80 °C / Inert atmosphere 2: pyrrolidine / toluene / 20 °C / Inert atmosphere View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 51, # 21 p. 5110 - 5113
