1-溴-3-(溴甲基)-5-甲氧基苯合成路线 （共 3 条）
反应条件
N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in tetrachloromethane
12 h; Reflux;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BRENNEMAN, Jehrod Burnett; GINN, John; LOWE, Michael D.; SARKO, Christopher Ronald; TASBER, Edward S.; ZHANG, Zhonghua
Patent: US2014/73629 A1, 2014 ;
Location in patent: Paragraph 0298; 0299; 0314 ;
反应条件
phosphorus tribromide in dichloromethane
T=0 - 20°C; 0.166667 h;
参考文献
Roche Palo Alto LLC
Patent: US2004/186092 A1, 2004 ;
Location in patent: Page/Page column 21 ;
US 20040186092 A1
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 24 h / 20 °C
2: N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile / tetrachloromethane / 12 h / |Reflux
View Scheme
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BRENNEMAN, Jehrod Burnett; GINN, John; LOWE, Michael D.; SARKO, Christopher Ronald; TASBER, Edward S.; ZHANG, Zhonghua
Patent: US2014/73629 A1, 2014 ;
