1: in methanol; water
2 h;
2: With hydrogenchloride; water
8 h; Reflux;
参考文献
Lyra, Bruno F.; De Morais, Soraya A.; Rocha, Gerd B.; Miller, Joseph; Moura, Gustavo L.C.; Simas, Alfredo M.; Peppe, Clovis; De Athayde-Filhoa, Petronio F.
Journal of the Brazilian Chemical Society, 2010 , vol. 21, # 5 p. 934 - 940
1: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine in dichloromethane
T=20°C; 3 h;
2: With water in dichloromethane
参考文献
KARO BIO AB
Patent: WO2007/3419 A1, 2007 ;
Location in patent: Page/Page column 69-72 ;
WO 2007/003419 A1