n-butyllithium in tetrahydrofuran; hexane boronic ester and ICH2Cl in rigorously dried THF cooled to -78°Cand stirred under Ar during dropwise addn. of 1.6 M n-BuLi in hexane, kept overnight at 20-25°C; concd. in vac., treated with petroleum ether and concd. aq. NH4Cl, org.phase dried over MgSO4, distilled bulb to bulb in vac.;
hydrogenchloride; methyllithium in tetrahydrofuran T=-78 - 20°C; P=0.1 Torr;
参考文献
Barluenga, Jose; Fernandez-Simon, Jose L.; Concellon, Jose M.; Yus, Miguel
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 3339 - 3344
n-butyllithium in tetrahydrofuran; hexane boronic ester and ICH2Cl in rigorously dried THF cooled to -78°Cand stirred under Ar during dropwise addn. of 1.6 M n-BuLi in hexane, kept overnight at 20-25°C; concd. in vac., treated with petroleum ether and concd. aq. NH4Cl, org.phase dried over MgSO4, distilled bulb to bulb in vac.;
参考文献
Sadhu, Kizhakethil Mathew; Matteson, Donald S.
Organometallics, 1985 , vol. 4, p. 1687 - 1689
