4-硝基吡咯-2-羧酸乙酯合成路线 （共 18 条）
反应条件
triethylamine in ethanol T=20°C; 168 h;
参考文献
Nishiwaki, Nagatoshi; Ogihara, Takuma; Takami, Toshiko; Tamura, Mina; Ariga, Masahiro
Journal of Organic Chemistry, 2004 , vol. 69, # 24 p. 8382 - 8386
反应条件
sodium hydroxide in ethanol; water T=50°C; 1 h;
参考文献
Lee; Coulter; Lown
Journal of Organic Chemistry, 1988 , vol. 53, # 9 p. 1855 - 1859
反应条件
triethylamine in ethanol T=20°C; 16 h;
参考文献
BAYER HEALTHCARE AG
Patent: WO2004/52852 A1, 2004 ;
Location in patent: Page 31-32 ;
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile T=20°C; Condensation; 7 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 6 p. 995 - 998
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile T=20°C; Condensation; 4 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 6 p. 995 - 998
反应条件
1: HNO3(fuming); H2SO4 / acetic anhydride 2: NaH View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 8, # 8 p. 1947 - 1955
反应条件
potassium hydroxide T=100°C; 19 h;
参考文献
Wakabayashi, Ken-Ichi; Miyachi, Hiroyuki; Hashimoto, Yuichi; Tanatani, Aya
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 8 p. 2837 - 2846
反应条件
1: 100 percent / aq. KOH / 19 h / 100 °C 2: oxalyl chloride / CH2Cl2; dimethylformamide / 4.5 h / 20 °C View Scheme
参考文献
Lee; Coulter; Lown
Journal of Organic Chemistry, 1988 , vol. 53, # 9 p. 1855 - 1859
反应条件
sodium hydride in N,N-dimethyl-formamide T=20°C; 0.5 h;
参考文献
Wakabayashi, Ken-ichi; Imai, Keisuke; Miyachi, Hiroyuki; Hashimoto, Yuichi; Tanatani, Aya
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 14 p. 6799 - 6812
参考文献
Firoozi; Javidnia; Kamali; Fooladi; Foroumadi; Shafiee
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 1 p. 123 - 128
