1,4,5,6-四氢环戊并吡唑-3-甲酸合成路线 （共 5 条）
反应条件
potassium hydroxide in methanol; water T=43°C; 1.5 h;
参考文献
Wilson, Robert D.; Cleator, Ed; Ashwood, Michael S.; Bio, Matthew M.; Brands, Karel M.J.; Davies, Antony J.; Dolling, Ulf-H; Emerson, Khateeta M.; Gibb, Andrew D.; Hands, David; McKeown, Arlene E.; Oliver, Steven F.; Reamer, Robert A.; Sheen, Faye J.; Stewart, Gavin W.; Zhou, George X.
Organic Process Research and Development, 2009 , vol. 13, # 3 p. 543 - 547
反应条件
1: EtONa / ethanol / 18 h / 20 °C 2: N2H4*H2O; AcOH / 8 h / Heating 3: 42 percent / aq. NaOH / dioxane / 18 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 18 p. 3945 - 3951
反应条件
1: ethanol; N2H4 / anschliessendes Behandeln mit wss.NH3 2: ethanolic KOH View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 536, p. 97,108
反应条件
1,1'-carbonyldiimidazole in tetrahydrofuran T=20 - 60°C; 1 h;
参考文献
Wilson, Robert D.; Cleator, Ed; Ashwood, Michael S.; Bio, Matthew M.; Brands, Karel M.J.; Davies, Antony J.; Dolling, Ulf-H; Emerson, Khateeta M.; Gibb, Andrew D.; Hands, David; McKeown, Arlene E.; Oliver, Steven F.; Reamer, Robert A.; Sheen, Faye J.; Stewart, Gavin W.; Zhou, George X.
Organic Process Research and Development, 2009 , vol. 13, # 3 p. 543 - 547
反应条件
copper unter Wasserstoff;
参考文献
v. Auwers; Noll
Justus Liebigs Annalen der Chemie, 1938 , vol. 536, p. 97,108
