反应条件
1: 1) n-BuLi / 1) THF, hexane, -45 deg C, 1.5 h; 2) r.t., water
2: 1) n-BuLi / 1) THF, hexane, 0 deg C, 1 h; 2) -78 deg C, r.t., 1 h, water
3: 85 percent / aq. HCl / 24 h / Heating
4: acetyl chloride / acetone / 0.5 h / Ambient temperature
5: 1) NaH / 1) mineral oil, THF, 0 deg C, 3 min; 2) THF, 0 deg C, 20 min, r.t., 30 min
6: 49 percent / acetic acid; CH2Cl2
7: trifluoroacetic acid, water / 15 h / 55 °C
View Scheme
参考文献
Tamura, Yasumitsu; Sasho, Manabu; Akai, Shuji; Wada, Akimori; Kita, Yasuyuki
Tetrahedron, 1984 , vol. 40, # 22 p. 4539 - 4548
