3-磺酰氨基-2-噻吩甲酸甲酯合成路线 （共 11 条）
反应条件
ammonia in dichloromethane T=0°C; 2 h;
参考文献
Vega, Salvador; Madronero, Ramon; Diaz, J. Antonio; Junquera, Francisco; Alonso, Javier; et al.
European Journal of Medicinal Chemistry, 1988 , vol. 23, p. 329 - 334
反应条件
1.1: NaNO2; glacial acetic acid; aq. HCl / 1 h / 0 °C 1.2: SO2; CuCl2 / acetic acid / 1 h / 0 °C 2.1: aq. NH3 / acetone / 1 h View Scheme
参考文献
Pesticide Science, , vol. 40, # 4 p. 293 - 297
反应条件
pH 4 buffer; water T=28°C; var pH; Rate constant;
参考文献
Journal of Agricultural and Food Chemistry, , vol. 44, # 1 p. 333 - 337
反应条件
pH 4 buffer; water T=28°C; var pH; Rate constant;
参考文献
Journal of Agricultural and Food Chemistry, , vol. 44, # 1 p. 333 - 337
反应条件
1: 85 percent / 2M NaOMe / methanol / 24 h / Heating 2: 42 percent / PCl5 View Scheme
参考文献
Vega, Salvador; Madronero, Ramon; Diaz, J. Antonio; Junquera, Francisco; Alonso, Javier; et al.
European Journal of Medicinal Chemistry, 1988 , vol. 23, p. 329 - 334
反应条件
1: 85 percent / 2M NaOMe / methanol / 24 h / Heating 2: 44 percent / PCl5 View Scheme
参考文献
Vega, Salvador; Madronero, Ramon; Diaz, J. Antonio; Junquera, Francisco; Alonso, Javier; et al.
European Journal of Medicinal Chemistry, 1988 , vol. 23, p. 329 - 334
反应条件
1: 85 percent / 2M NaOMe / methanol / 24 h / Heating
2: 42 percent / PCl5
View Scheme
参考文献
Vega, Salvador; Madronero, Ramon; Diaz, J. Antonio; Junquera, Francisco; Alonso, Javier; et al.
European Journal of Medicinal Chemistry, 1988 , vol. 23, p. 329 - 334
反应条件
1: With sulfuric acid; acetic acid; sodium nitrite
T=5°C; Diazotization; 0.166667 h;
2: With copper(l) chloride; sodium nitrite in water
T=20°C; Substitution; 0.166667 h;
参考文献
Bastide; Badon; Cambon; Vega
Pesticide Science, 1994 , vol. 40, # 4 p. 293 - 297
反应条件
1.1: NaNO2; aq. H2SO4; acetic acid / 0.17 h / 5 °C
1.2: 2 percent / NaNO2; CuCl / H2O / 0.17 h / 20 °C
2.1: pig liver esterase / aq. phosphate buffer / pH 7 / Enzymatic reaction
View Scheme
参考文献
Bastide; Badon; Cambon; Vega
Pesticide Science, 1994 , vol. 40, # 4 p. 293 - 297
反应条件
sodium methylate in methanol
24 h; Heating;
参考文献
Vega, Salvador; Madronero, Ramon; Diaz, J. Antonio; Junquera, Francisco; Alonso, Javier; et al.
European Journal of Medicinal Chemistry, 1988 , vol. 23, p. 329 - 334
