4-(4-氟苯基)-1,2,3,4-四氢-6-甲基-2-氧代-5-嘧啶羧酸乙酯合成路线 (共 7 条)
反应条件
graphite in neat (no solvent)
T=70°C; 2 h; Green chemistry;
参考文献
Dhumaskar, Kashinath L.; Meena, Surya Nandan; Ghadi, Sanjeev C.; Tilve, Santosh G.
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 13 p. 2897 - 2899
反应条件
ZnO
T=60°C; Biginelli Pyrimidone Synthesis; 12 h;
参考文献
Tamaddon, Fatemeh; Moradi, Somayeh
Journal of Molecular Catalysis A: Chemical, 2013 , vol. 370, p. 117 - 122
反应条件
1: 1-fluoro-4-hydroxymethylbenzene With Bi(NO3)3 in various solvent(s)
T=50°C; 0.0833333 h;
2: ethyl acetoacetate; urea in various solvent(s)
T=90°C;
参考文献
Khosropour, Ahmad R.; Khodaei, Mohammd M.; Beygzadch, Mojtaba; Jokar, Mahbubeh
Heterocycles, 2005 , vol. 65, # 4 p. 767 - 773
反应条件
1: 1-(chloromethyl)-4-fluorobenzene With Bi(NO3)3; tetrabutyl ammonium fluoride
T=120°C;
2: ethyl acetoacetate; urea T=120°C; Biginelli reaction;
参考文献
Khodaei, Mohammad Mehdi; Khosropour, Ahmad Reza; Jowkar, Mahbubeh
Synthesis, 2005 , # 8 art. no. Z21704SS, p. 1301 - 1304
参考文献
Salehi, Peyman; Dabiri, Minoo; Zolfigol, Mohammad Ali; Baghbanzadeh, Mostafa
Heterocycles, 2005 , vol. 65, # 5 p. 1177 - 1181
反应条件
Bi(NO3)3
T=100°C; Biginelli reaction; 0.333333 h;
参考文献
Khosropour, Ahmad R.; Khodaei, Mohammad M.; Beygzadeh, Mojtaba
Heteroatom Chemistry, 2007 , vol. 18, # 6 p. 684 - 687
反应条件
Bi(NO3)3*ZnCl2*Al2O3
T=140°C; 0.333333 h; microwave irradiation;
参考文献
Singh, Jagjeet; Koui, Summon; Pannu, Ajay P. S.; Sharma, Rattan L.; Razdan, Tej K.
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 2 p. 349 - 357